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Higher Reliance on Glycolysis Limits Glycolytic Responsiveness in Degenerating Glaucomatous Optic Nerve
Molecular Neurobiology
Jassim AH, Coughlin L, Harun-Or-Rashid M, Kang PT, Chen Y-R, Inman DM
DOI: 10.1007/s12035-019-1576-4 -
Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension
Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):1-15
Jassim AH, Inman DM
DOI: 10.1167/iovs.18-24977 -
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma
J Neuroinflammation 2018 Nov 13;15(1):313
Harun-Or-Rashid M, Inman DM
DOI: 10.1186/s12974-018-1346-7 -
Changes in ganglioside GM1 expression in glaucomic retina
J Neurosci Res 2018 Oct;96(10):1627-1630
Pappenhagen N, Inman DM
DOI: 10.1002/jnr.24273 -
Structural and Functional Rescue of Chronic Metabolically Stressed Optic Nerves through Respiration
J Neurosci, 2018 May 30;38(22):5122-5139
Harun-Or-Rashid M, Pappenhagen N, Palmer PG, Smith MA, Gevorgyan V, Wilson GN, Crish SD, Inman DM
DOI: 10.1523/JNEUROSCI.3652-17.2018 -
Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma
Front Neurosci, 2017 Mar 30;11:146
Inman DM, Harun-Or-Rashid M
DOI: 10.3389/fnins.2017.00146 -
Persistence of intact retinal ganglion cell terminals after axonal transport loss in the DBA/2J mouse model of glaucoma
J Comp Neurol, 2016 Dec 1;524(17):3503-3517
Smith MA, Xia CZ, Dengler-Crish CM, Fening KM, Inman DM, Schofield BR, Crish SD
DOI: 10.1002/cne.24012 -
Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma
Front Neurosci, 2016 Nov 3;10:494
Wilson GN, Smith MA, Inman DM, Dengler-Crish CM, Crish SD -
Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma
Exp Eye Res, 2016 Sep;150:22-33
Cooper ML, Crish SD, Inman DM, Horner PJ, Calkins DJ
DOI: 10.1016/j.exer.2015.11.016 -
Decreased Energy Capacity and Increased Autophagic Activity in Optic Nerve Axons With Defective Anterograde Transport
Invest Ophthalmol Vis Sci, 2015 Dec;56(13):8215-27
Kleesattel D, Crish SD, Inman DM
DOI: 10.1167/iovs.15-17885 -
Heterogeneous Ganglioside Standards in LC-MS/MS: Sensitive Method for Quantifying the Major Molecular Components in Mono-Sialo Ganglioside Standards
J Anal Bioanal Tech, S13:009, 2015 Nov
Gobburi ALP, Zhang R, Willard B, Inman D, Anderson DJ
DOI: 10.4172/2155-9872.S13-009 -
Early pro-inflammatory cytokine elevations in the DBA/2J mouse model of glaucoma
J Neuroinflammation, 2015 Sep 17;12:176
Wilson GN, Inman DM, Dengler Crish CM, Smith MA, Crish SD
DOI: 10.1186/s12974-015-0399-0 -
Mitochondrial morphology differences and mitophagy deficit in murine glaucomatous optic nerve
Invest Ophthalmol Vis Sci, 2015 Feb 5;56(3):1437-46
Coughlin L, Morrison RS, Horner PJ, Inman DM
DOI: 10.1167/iovs.14-16126 -
Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma
Front Neurosci, 2014 Sep 17;8:290
Dengler-Crish CM, Smith MA, Inman DM, Wilson GN, Young JW, Crish SD
DOI: 10.3389/fnins.2014.00290 -
ADME and Ocular Therapeutics: Retina [Chapter 12]
Methods in Pharmacology and Toxicology: Ocular Pharmacology and Toxicology, Edited by: Brian C. Gilger, 2014, ISBN 978-1-62703-744-0
CJ Van der Schyf, SD Crish, C Crish, D Inman, WJ Geldenhuys
DOI: DOI 10.1007/7653_2013_12 -
Differential progression of structural and functional alterations in distinct retinal ganglion cell types in a mouse model of glaucoma
J Neurosci, 2013 Oct 30;33(44):17444-57
Della Santina L, Inman DM, Lupien CB, Horner PJ, Wong RO
DOI: 10.1523/JNEUROSCI.5461-12.2013 -
α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction
PLoS One, 2013 Jun 5;8(6):e65389
Inman DM, Lambert WS, Calkins DJ, Horner PJ
DOI: 10.1371/journal.pone.0065389 -
Early reduction of microglia activation by irradiation in a model of chronic glaucoma
PLoS One, 2012;7(8):e43602
Bosco A, Crish SD, Steele MR, Romero CO, Inman DM, Horner PJ, Calkins DJ, Vetter ML
DOI: 10.1371/journal.pone.0043602 -
Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration
J Neurosci, 2010 Apr 21;30(16):5644-52
Baltan S, Inman DM, Danilov CA, Morrison RS, Calkins DJ, Horner PJ
DOI: 10.1523/JNEUROSCI.5956-09.2010 -
Distal axonopathy with structural persistence in glaucomatous neurodegeneration
Proc Natl Acad Sci U S A, 2010 Mar 16;107(11):5196-201
Crish SD, Sappington RM, Inman DM, Horner PJ, Calkins DJ
DOI: 10.1073/pnas.0913141107 -
Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons
Exp Neurol, 2009 Aug;218(2):274-85
Uo T, Dworzak J, Kinoshita C, Inman DM, Kinoshita Y, Horner PJ, Morrison RS
DOI: 10.1016/j.expneurol.2009.05.010 -
Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma
J Neurosci, 2008 Mar 12;28(11):2735-44
Buckingham BP, Inman DM, Lambert W, Oglesby E, Calkins DJ, Steele MR, Vetter ML, Marsh-Armstrong N, Horner PJ
DOI: 10.1523/JNEUROSCI.4443-07.2008 -
Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma
Invest Ophthalmol Vis Sci, 2008 Apr;49(4):1437-46
Bosco A, Inman DM, Steele MR, Wu G, Soto I, Marsh-Armstrong N, Hubbard WC, Calkins DJ, Horner PJ, Vetter ML
DOI: 10.1167/iovs.07-1337 -
Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model
J Neurosci, 2008 Jan 9;28(2):548-61
Soto I, Oglesby E, Buckingham BP, Son JL, Roberson ED, Steele MR, Inman DM, Vetter ML, Horner PJ, Marsh-Armstrong N
DOI: 10.1523/JNEUROSCI.3714-07.2008 -
Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma
Glia, 55(9):942-953
Inman DM, Horner PJ
DOI: 10.1002/glia.20516 -
Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma
Invest Ophthalmol Vis Sci, 2006 Mar;47(3):977-85
Steele MR, Inman DM, Calkins DJ, Horner PJ, Vetter ML -
Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma
Invest Ophthalmol Vis Sci, 2006 Mar;47(3):986-96
Inman DM, Sappington RM, Horner PJ, Calkins DJ -
Treatment with the neurosteroid dehydroepiandrosterone promotes recovery of motor behavior after moderate contusive spinal cord injury in the mouse
J Neurosci Res, 2004 Feb 1;75(3):391-400
Fiore C, Inman DM, Hirose S, Noble LJ, Igarashi T, Compagnone NA -
Ascending sensory, but not other long-tract axons, regenerate into the connective tissue matrix that forms at the site of a spinal cord injury in mice
J Comp Neurol, 2003 Aug 4;462(4):431-49
Inman DM, Steward O -
Physical size does not determine the unique histopathological response seen in the injured mouse spinal cord
J Neurotrauma, 2003 Jan;20(1):33-42
Inman DM, Steward O -
Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of mice
J Comp Neurol, 2002 Sep 23;451(3):225-35
Inman D, Guth L, Steward O -
Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models
Exp Neurol, 1999 May;157(1):19-42
Steward O, Schauwecker PE, Guth L, Zhang Z, Fujiki M, Inman D, Wrathall J, Kempermann G, Gage FH, Saatman KE, Raghupathi R, McIntosh T -
Manipulating Glia to Protect Retinal Ganglion Cells in Glaucoma [Chapter]
Glaucoma - Current Clinical and Research Aspects, Pinakin Gunvant (Ed.), ISBN: 978-953-307-263-0, InTech
DM Inman, CB Lupien and PJ Horner